Verdict: pre-implantation genetic diagnosis only in the case of serious hereditary diseases

VGH Munich: comparison of scale Duchenne muscular dystrophy

Pre-implantation diagnosis (PID) is only in the case of particularly serious genetic disorders is permitted. Scale is the weakness of an inherited severe muscle, specifically the muscle dystrophy of type Duchenne, such as the Bavarian administrative court (VGH) in Munich, Germany on Friday, 15. March 2019, delivered the judgment of the previous day decided (Az.: 20 B 17.1507).

Duchenne muscular dystrophy is inherited from the mother, usually to sons, without the mother herself was ill. By the disease the important muscle is made of protein Dystrophin; Muscle fibers are replaced gradually by fat. This leads to Muscle degeneration and usually in young adulthood to death.

The VGH Munich was now clear that the Bavarian ethics Committee of a PID only in the case of “serious Erbkrankheiten“ agree to could. In the embryo protection act, the legislature had classified the Duchenne muscular dystrophy as a serious genetic disease. Therefore, it could be used for comparison. Turn off is “always on the expected Severity of the disease and the associated effects on the Eltern“.

In the event of a dispute, the father is suffering from Myotoner dystrophy. The hereditary disease is associated with a delayed relaxation of the muscles and also a muscular weakness.

To this end, the VGH stressed that this disease “in various degrees of severity occur kann“. As a “schwerwiegend“ for the purposes of the embryo protection act, only the “congenital Myotonic Dystrophie&#8220 but; view, mostly starting from birth, most severe impairments occur. This is not a high risk in this specific case, but, as this Form will almost inherited exclusively through the mother, not here alone, preloaded father. Therefore, the VGH rejected the parents ‘ request for a PID. mwo/fle